Other Names
Silybum marianum, Milk Thistle.
What it is
This ingredient is a flavonoid mixture naturally extracted from the fruits and seeds of Silybum marianum plant. It helps to protect the skin against oxidative damage caused by free radicals, environmental pollution and UV radiation. It possesses anti-inflammatory and anti-immunomodulatory properties. Also, used as an oral health supplement.
Mode of usage pertaining to the discussion below
Topical application in cosmetics and personal care products.
Safety Profile (Based on regional guidelines)
| European Union – CIR | Data unavailable |
| European Union – SCCS | Data unavailable |
| US FDA | Data unavailable |
| ASEAN guidelines | Data unavailable |
Safety in special situations
PregnancyThe topical form is not listed as an ingredient to be avoided by pregnant women based on currently available data
Nursing MothersThe topical form is not listed as an ingredient to be avoided by nursing women based on currently available data
Babies under 2 yearsSilymarin is used orally in newborn babies for jaundice, and hence the topical application may be considered safe for babies
Children under 12 yearsSilymarin is used orally in children to improve liver function in selected disease states, and hence the topical application may be considered safe for this population
Cancer freeSilymarin has been used orally in individuals with cancer for several outcomes, and hence the topical application may be considered safe for use in this population
Environmental and Ecological Concerns
Vegan
Biodegradable
Ecotoxicity
Natural/Synthetic
Attributes
ComedogenicityNot listed as an ingredient to be comedogenic based on currently available data
Acne prone skinSafe for use
Sensitive skinSafe for use
Note
- Silymarin is not listed as an ingredient to be avoided by persons with acne prone or sensitive skin based on currently available data.
Conclusion Silymarin is safe as per current practice of use.
References
- https://pubchem.ncbi.nlm.nih.gov
- https://european-union.europa.eu
- Drugs and Lactation Database (LactMed®). Bethesda (MD): National Institute of Child Health and Human Development.
- https://www.cancer.gov
- https://jag.journalagent.com
- https://pubmed.ncbi.nlm.nih.gov
- Karimzadeh, 2024, Molecular Biology Reports.
Disclaimer
The above information is based on ongoing toxicology research at CHOSEN®'s R&D. We will do our best to update the information as and when the latest studies are available. If you have any inputs regarding the above information, please email us at ingredients@chosenstore.in