In fifteen seconds
Diisopropyl Sebacate is a lightweight cosmetic ingredient that helps give skincare formulations a smooth and comfortable feel.
What it is used for
Diisopropyl Sebacate is used as an emollient, skin conditioning agent, solvent and plasticiser in cosmetic formulations. It helps soften the skin, improve the application of the product and support the incorporation of other ingredients.
Special Populations
| Group | Our Position |
| Pregnancy | There is no known pregnancy specific concern with diisopropyl sebacate in topical cosmetic use. |
| Nursing mothers | No specific concern has been identified with using diisopropyl sebacate on the skin while breastfeeding. |
| Babies (under 1 year) | Based on the available information, diisopropyl sebacate has no stated limits on use in skincare for babies under 1 years of age. |
| Children | There are no known specific restrictions on using diisopropyl sebacate on the skin of children. |
| Cancer history | There is no known concern with using diisopropyl sebacate on your skin if you have a personal or family history of cancer. |
| Women with hormonal issues (PCOS, thyroid, menopause) | There is no known concern with using diisopropyl sebacate on the skin in women with PCOS, thyroid and menopause. |
Regulatory status
| Jurisdiction | Status |
| United States (CIR) | Safe to use, as per current practice |
| European Union (SCCS) | No specific data |
| United States (FDA) | No specific data |
| ASEAN Cosmetic Directive (ACD) | No specific data |
Why it is in our formulas
Diisopropyl Sebacate is included to improve the sensory performance and overall elegance of the formulation. It helps formulations spread easily over the skin and contributes to a smooth, lightweight after feel.
Environmental and Ecological Concerns
| Parameter | Status |
| Vegan | Yes. |
| Natural/Synthetic | This ingredient can come from natural sources or be made synthetically. If you’d like to know which version is in your product, check the product label or ask the brand. |
| Biodegradable | Yes. |
| Ecotoxicity | No specific ecotoxicity concern was identified based on currently available data. |
Attributes
| Attribute | Status |
| Comedogenicity | This ingredient is not known to clog pores. |
| Acne prone skin | No specific concern for acne prone skin was identified based on currently available data. |
| Sensitive skin | No specific concern for sensitive skin was identified based on currently available data. |
Conclusion: Diisopropyl Sebacate is considered safe as per the current practices of use.
Questions people ask
Is Diisopropyl Sebacate an oil?
Diisopropyl Sebacate is an ester ingredient rather than a conventional plant oil. It is commonly used in cosmetic formulations for its emollient and skin conditioning properties.
Is Diisopropyl Sebacate used in sunscreen products?
Yes. Diisopropyl Sebacate can be used in sunscreen formulations as a cosmetic emollient and solvent, depending on the formulation.
Does Diisopropyl Sebacate help sunscreen spread evenly?
Yes. Its emollient properties can help improve the application and distribution of sunscreen formulations across the skin.
What is the difference between Diisopropyl Sebacate and Diisopropyl Adipate?
They are different ester ingredients with different chemical structures. Both may be used as emollients and solvents in cosmetic formulations.
Is Diisopropyl Sebacate suitable for lightweight formulations?
Yes. Its sensory properties make it suitable for formulations where a smooth, lightweight and comfortable skin feel is desired.
References
- Cosmetic Ingredient Review (CIR). Final Report of the Cosmetic Ingredient Review Expert Panel on the Safety Assessment of Dicarboxylic Acids, Salts, and Esters. International Journal of Toxicology. 2012;31(Suppl 1):5–76.
- COSMILE Europe. Diisopropyl Sebacate.
- NCBI. PubChem. Diisopropyl Sebacate.
Last updated: 01-Oct-2026
Disclaimer
The above information is based on ongoing toxicology research and scientific review by the CHOSEN® R&D team. We aim to update this information as new and relevant scientific evidence becomes available. If you have any inputs or suggestions regarding the information above, please email us at ingredients@chosenstore.in.