CINOXATE

Also known as: 2-ethoxy ethyl 4-methoxycinnamate,  2 -EMC

CINOXATE

What it is

Cinoxate is a UVB filter in sunscreen formulations. However, its use has decreased over time as newer-generation UV filters with broader-spectrum protection and better stability have become more prevalent in sunscreen formulations.

Mode of usage pertaining to the discussion below

Topical application in cosmetics and personal care products.

Safety in special situations

Pregnancy Not recommended for use by pregnant women

Nursing Mothers Not recommended for use by nursing mothers

Babies under 2 years Not recommended for babies

Children under 12 years Not recommended for children

Individuals with cancer history/risk Not recommended for people with a history of or at risk of cancer

Environmental and Ecological Concerns

Vegan

Natural/Synthetic

Biodegradable Not readily biodegradable

Ecotoxicity Potentially ecotoxic

Attributes

Comedogenicity Not listed as an ingredient to be comedogenic based on currently available data

Acne prone skin Not listed as an ingredient to be avoided by people with acne prone skin based on currently available data

Sensitive skin May not be safe based on currently available data

Note

  • Cinoxate is a rare photoallergen.

Safety Profile (Based on regional guidelines)

European Union – CIR Data unavailable
European Union – SCCS Data unavailable
US FDA Listed as Non-GRASE (Not generally recognized as safe and effective) Category III
ASEAN guidelines No available data

Conclusion Cinoxate is not currently approved by any regional guidelines, and its safety remains inconclusive.

References

  • https://www.accessdata.fda.gov
  • https://assets.publishing.service.gov.uk
  • https://pubmed.ncbi.nlm.nih.gov

Disclaimer

The above information is based on ongoing toxicology research at CHOSEN®’s R&D. We do our best to update the information as and when the latest studies are available. If you have any inputs regarding the above information, please email us at ingredients@chosenstore.in